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ȣ - 510223 8 |
Difference of LV synchrony according to the pacing sites with RV apex, mid-septum, RVOT in normal subjects |
가톨릭의대 대전성모병원 |
윤희정, 진승원, 허성호, 이종민, 김지훈, 장성원, 신우승, 오용석, 이만영, 승기배, 노태호, 김재형, 최규보 |
Backgroud : The synchrony of pacing heart may be affected by RV pacing site and important in pacemaker patients for cardiac function. The mechanism of dyssynchrony includes regional delays of both ventricular contraction and relaxation. Dyssynchrony may be inter- or intraventricular, and echocardiography may evaluate both types through several techniques. We evaluated the difference of LV synchrony according to RV pacing sites (RV apex, mid-septum and RVOT) in normal systolic functioned patients with narrow QRS. Methods : We performed in 18 patients (8 men, 10 women; age, 49.5 ± 13.7 years) paing at RV apex, interventricular mid-septum and RVOT. Transthoracic echocardiography at rest and during pacing were performed in all patients. Pacing rate was 600msec. We measured both interventricular and intraventricular dyssynchrony by echocardiography. Interventricular dyssynchrony was performed by measuring the time between ventricular ejections (the time interval between the beginning of the systolic wave of pulmonary and aortic ejection) and by measuring the time between septal contraction and posterior wall contraction though the M-mode. Intraventricular dyssynchrony was performed by measuring the time between the beginning of the QRS complex and the peak systolic wave of tissue Doppler (between the septal and lateral basal wall). Results : Results are presented in Table 1. Conclusion : The RVA pacing is superior to mid-septum and RVOT pacing for intraventricular synchrony in normal systolic functioned patients with narrow QRS.
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Table 1. Echocardiographic LV synchrony according to the pacing
sites
LV synchrony
|
RVA
pacing |
Mid-septum
pacing |
RVOT
pacing |
P value
a |
P value
b |
P value
c |
Intraventricular
QSI measure
(msec) |
59.1±29.8 |
75.3±32.3
|
76.9±35.5 |
0.037 |
0.019 |
0.854 |
Interventricular
M-Mode
(msec) |
76.8±28.5 |
94.1±34.4 |
92.4±33.4 |
0.093 |
0.084 |
0.896 |
Doppler (msec) |
42.6±13.0 |
45.9±11.0 |
55.2±25.5 |
0.301 |
0.061 |
0.170 |
a RVA pacing vs mid-septum pacing,
b RVA pacing vs
RVOT pacing, c Mid-septum
pacing vs RVOT pacing
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