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Predictive power of preoperative non-stress echocardiographic evaluation for postoperative cardiovascular events in noncardiac surgery
성균관대학교 의과대학 삼성서울병원 심장혈관센터 순환기내과¹ , 응급의학과²
조수진¹, 최진호² , 최진오¹ ,한주용¹ , 최승혁¹ , 온영근¹ , 이상철¹ , 성지동¹ , 권현철¹ , 박승우¹ , 김준수¹ , 전은석¹ , 김덕경¹ , 이상훈¹ , 홍경표¹ , 박정의¹
Background and Objectives Although non-stress echocardiography is widely performed as preoperative screening before noncardiac surgery, its predictive power for postoperative cardiac complication is not well shown. We investigated whether echocardiographic findings could identify patients at high risk for postoperative cardiovascular events after elective noncardiac surgery. Methods and Results We enrolled 1,113 patients (age 64±11 year, male 64%) who were referred for cardiovascular risk evaluation before elective noncardiac surgery and underwent Doppler echocardiography within 3 months. Patients with significant mitral valvular heart disease or who were not suitable for tissue Doppler analysis were excluded. Clinical preoperative cardiovascular risk was assessed using the Revised Cardiac Risk Index (RCRI).Postoperative major adverse cardiovascular events (MACE) were defined by cardiac death, myocardial infarction, or aggravation of congestive heart failure within postoperative 72 hours.Postoperative MACE occurred in 97 patients (8.7%). Receiver-operating characteristic (ROC) analysis showed that any echocardiographic parameters (AUC=0.618) could not reach comparable predictive power to RCRI (0.677). Subgroup analysis revealed that LAVI (AUC=0.683) and E/e` (0.727) was more predictive for MACE than RCRI (0.573) in patients younger than 60 years (Table 1). Conclusions Routine preoperative Doppler echrocardiography adjunct to clinical evaluation added little value for the prediction of postoperative MACE after noncardiac surgery. However, it might have a role in young age subgroup in which RCRI was less predictive than old age subgroup.
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Table 1. ROC analysis: postoperative major cardiovascular events

Age (yr)

Total  (n=1113)

Age < 60  (n=301)

Age ≥ 60  (n=812)

 

AUC

P Value

AUC

P Value

AUC

P value

RCRI

0.677

<0.001*

0.573

0.277

0.658

<0.001*

LVEF

0.609

0.004*

0.585

0.204

0.567

0.053

RWMA

0.618

0.002*

0.574

0.269

0.590

0.010*

E/e’

0.559

0.118

0.683

0.006*

0.520

0.571

LAVI

0.593

0.014*

0.727

0.001*

0.521

0.538

 

   



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