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Clinical consequence of stenting in variant angina with fixed stenotic lesion
성균관대학교 의과대학 삼성서울병원 심장혈관센터 순환기내과¹ ,응급의학과²
이상엽¹, 최진호¹ ² ,최승민¹ ,한주용¹ ,최승혁¹,권현철 ¹ ,이상훈¹ ,홍경표¹ ,박정의¹
Background: Data regarding the clinical consequence of stenting for significant fixed lesion accompanying vasospasm is still limited. Methods: We investigated clinical consequence of 66 lesions from 66 consecutive patients who underwent elective stenting for significant fixed lesion accompanying vasospasm. The lesion was defined by (1) intracoronary ergonovine-induced tight stenosis with diminution of previously normal anterograde coronary flow less than TIMI 3 and typical angina pain or corresponding EKG change, and (2) recovery of TIMI 3 flow after nitroglycerin infusion but residual diameter stenosis > 75%. Patients with spontaneous spasm without provocation were excluded. In all patients, MACE was investigated by clinical records and telephone interview. Results: There was no difference of clinical characteristics and frequency of multivessel disease between BMS (N=43) and DES (N=23) groups. During follow-up (interquartile range: 739 - 2332), clinically-driven coronary angiography was performed in 25 (58.1%) for BMS and 8 (34.8%) for DES groups. Cardiac death, TVF, TLR, and non-target vessel revascularization had developed in 2 (4.7%), 8 (18.6%), 6 (14.0%) 0 cases in BMS and 0, 2 (8.7%), 1 (4.3%), 2 (8.7%) in DES group (p=NS). MACE-free survival is shown below. Conclusion: Although the result is not completely free from limited number and retrospective selection bias, our data shows that intermediate results of stenting for variant angina with fixed lesion is favorable.
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