Background: Stent fractures(SF) are increasing problem in DES era, because local drug deliver did not reach in disrupted stent segment, after all result in neointimal overgrowth. Several risk factors ofSF were described from previous reports, the prevalence of SF in DES era is rarely known. Therefore, we investigated SF in consecutive series of cases in two centers. Method & result: Between June 2004 and December 2006, cases of SFs were collected from two centers(SNUH & SNUBH), respectively.SF was defined as angiographically visible interrupted connection of stent struts or fewer visible stent struts at the suspected site than normally looking stented area on intravascular ultrasound. 18 SFs were observed in 15 patients (3 fractures in 3 consecutive sirolimus eluting stent (SES), and 2 fractures in one SES). The incidence of fracture in SES was 0.60% (17fracture in 2842 SESs) and 0.05% (1 fracture in 1792 paclitaxel-eluting stents). Most cases (14 of 15) were detected at 6 month F/U CAG ,and only one case were detected at 18month F/U. The proportion of vessel distribution was 66.7% (Proximal to mid RCA :9 cases, dRCA :1 cases) in RCA, 20% in LCX, 13.3% in LAD, respectively. Binary restenosis occurred in 4 patients, and one patient of them was treated with paclitaxel eluting stent reinsertion, another with ballooning only, and the others with medical treatment after physiologic study (FFR),respectively. Remained 11 patients, who had only mild ISR when SF was discovered, were not associated adverse clinical outcome during F/U period (mean period 12month from SF detection).13 patients used adj. balloon after stent implantation and 7 of them used more than 16 atm for balloon inflation. All patients whose stents were post-dilated with high pressure more than 16atm did not show significant ISR during F/U period. Conclusion: Considering our experience, SFs in DES era don���t seem very serious problem. When stenting in tortous proximal RCA lesion, we must consider use of paclitaxel eluting stent. Indeed post-dialtion with high pressure balloon is a risk factor of SF to make a good stent apposition by using higher pressure balloon may reduce restenosis after fracture was occurred.