Introduction: The relationship between various geometry and pulsatility parameters of left ventricular vortex and conventional hemodynamic variables remains elusive Methods: Particle image velocimetry using contrast echocardiography with simultaneous LV pressure measurement was performed in 10 mongrel dogs during pharmacologic modulation of 棺-adrenergic receptor. A customized software (Omegaflow) was used to measure both average vortex geometric parameters (vortex depth [VD], length [VL], width [VW], and sphericity index [SI]) and vortex pulsatility parameters (relative strength [RS], vortex relative strength [VRS], and vortex pulsation [VPC]). Results: LV end-diastolic volume had positive correlation with VL (R=0.50, p=0.001) and VW (R=0.66 p<0.001), which did not show dose dependent change during inotrophic modulation. SI showed dose-dependent decreases with dobutamine infusion, whereas it did not change significantly during esmolol infusion. RS showed significant association with dP/dtmax (R=0.57, p<0.001) and Tau (R=-0.40, p<0.001) with dose-dependent change during inotrophic modulation. Other pulsatility parameters such as VRS and VPC showed similar results. Conclusion: Both LV geometry and hemodynamic variables affects vortex geometric and pulsatility parameters. Pulsatility parameters represent inotropic modulation more sensitively.