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ǥ : ȣ - 540380   17 
Long-term Outcomes of Elderly Patients with Acute Myocardial Infarction; Different Prognosis between ST elevation and non-ST elevation Myocardial Infarction
제주대학교병원
강동구, 현소영, 배재석, 김송이, 김기석, 주승재
Objectives Recently, elderly patients with acute myocardial infarction (AMI) are increasing rapidly, and some of them presented as non-ST elevation myocardial infarction (NSTEMI), but their long-term clinical outcomes are not well-defined in Korea. Methods From Nov 1st 2005 to Dec 31st 2008, 239 patients with AMI admitted to our hospital. They were divided into four aged groups; ≥75 (group 1), 65-74 (group 2), 50-64 (group 3), <50 years old (group 4). Results More patients with group 1 were women and non-smokers, and complained of atypical chest pain. Serum NT-proBNP level was higher, and hospital stays were longer in the group 1. Doppler echocardiographic study of the mitral inflow showed less restrictive filling pattern in the group 1. Previous histories of DM and ischemic heart disease, Killip classification, maximal CK-MB and troponin T level, left ventricular EF, and proportions of NSTEMI were not different among groups. 1-year survival, and major cardiovascular adverse event (MACE)-free survival were not significantly different (p=0.17, and 0.92, respectively). Subgroup analysis of patients with ST-elevation MI (STEMI) showed the lowest 1-year survival rate of group 1 (p=0.0067), but not patients with NSTEMI (p=0.46). Conclusions Elderly patients with AMI showed somewhat different clinical manifestations. Long-term survival rate was lower only in STEMI. Elderly patients with NSTEMI had similar long-term clinical outcomes.

 

Group 1

Group 2

Group 3

Group 4

p value

Female

53.1%

32.8%

14.1%

0%

<0.001

Hx of hypertension

65.0%

66.1%

58.3%

35.6%

0.007

Smoker

16.7%

38.7%

45.8%

75.6%

<0.001

Atypical Sx

25.0%

8.1%

4.2%

6.7%

0.001

Restrictive LV filling

15.6%

24.5%

39.0%

40.5%

0.022

NT-proBNP (pg/mL)

3583±4594

1088±1502

697±1858

332±635

<0.001

Hosp stay (days)

8.3±6.9

6.9±4.3

5.3±2.6

5.9±3.2

0.004

In-hosp mortality

13.3%

6.5%

9.7%

3.3%

0.38

1-yr survival

83.3%

91.9%

88.8%

95.6%

0.17

1-yr MACE-free survival

76.7%

75.8%

80.6%

77.8%

0.92

1-yr survival in STEMI

73.5%

90.9%

84.8%

100%

0.0067

1-yr survival in NSTEMI

96.2%

94.4%

96.2%

84.6%

0.46



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