Background: The benefits of the transradial approach have clearly been documented in numerous studies in the recent years. It allows earlier mobilization, reduced hospital stay and costs. There are some risks of vascular access site complications, even if it has lower risk compared with femoral approach. We investigated the complications of the transradial approach for coronary angiography(CAG) and percutaneous coronary intervention. Methods: Between Jan, 2001 and July, 2009, a total of 11591 patients were enrolled for coronary angiography in PNUH(2001-2008)& PNUYH(2009).We reviewed the complications of 9176 patients(79%) undergoing transradial approached CAG. We grouped those complications into two classes( Not-injuring and Injuring complications). Results: There were 528 complications(5.75%) of the transradial approach. Many of them were not-injuring type(4.25%). Radial artery spasm as not-injuring type, occurred in 390 patients(4.25%). Injuring complications occurred in 138 patients(1.5%).(Table) Conclusions: The complications appear to be not only infrequent and not significant compared with the femoral approach but also preventable with careful technique. Transradial approach seem to have a significant advance in CAG & PCI.