Background ; Contrast induced nephropathy (CIN) has been associated with increased in-hospital morbidity and mortality. However, considerable numbers of CIN patients recover their renal function within several days to several months without any sequelae. Moreover, the relationship of renal function after CIN to long-term adverse events (AEs) is still unknown. Objective ; To assess whether restoration of renal function after 1-3 month is affects on their long-term AEs or not. Method ; Database from the patients who underwent PCI from May 2008 to January 2010 were reviewed and we 471 identified patients who had follow-up serum Creatinine (sCr) within 1-3 months after PCI. CIN was defined as absolute increase of sCr > 0.5 or relative increase of > 25% within 72hrs after PCI. The CIN patients were classified as CIN-recover group (differences of sCr between baseline and FU sCr < 0.3 mg/dL, n=14) or CIN non-recover group (FU – Baseline sCr ��� 0.3, n=13). During 2yrs follow up, we assessed AEs included death, myocardial infarction, stroke, end-stage renal disease, percutaneous coronary revascularization, CABG and development of pulmonary edema. Result ; 72 (15.0%) of the 471 patients experienced AEs. The incidence of AEs was significantly higher in the CIN group (33.3%) than in the non-CIN group (13.9%) (p<0.001). Among the CIN patients, CIN recover group (14.3%) showed similar incidence of AEs compare with non-CIN group. On univariate analysis, there was significantly lower frequency of AEs in CIN recover group than CIN non-recover group. On multivariate analysis, the differences between baseline and follow-up sCr was considered as independent predictor of AEs (HR 1.759, p<0.001, 95% CI 1.301-2.378). Conclusion ; Development of CIN affected on long-term clinical course. However, the patients with recovered renal function after CIN within 1-3 months showed similar clinical course compared with non-CIN group. Follow-up sCr after CIN can be helpful method to identify high risk patients.