Purpose: The prognostic power of clinical parameters and imaging parameter in predicting cardiovascular outcome has not been compared in asymptomatic patients. Method: A total of 5,561 patients who had coronary CT and were followed for longer than 6 months on outpatient basis were included in the analysis. Clinical parameters included in the analysis were total cholesterol, LDL-cholesterol, creatinine, fasting blood sugar level, hs-CRP, urine microalbumin/creatinine ratio, homocysteine and NT-proBNP. Epicardial stenosis on coronary CT was analyzed as imaging parameter. Result: Of the total population, 3,3,87 (60.9%) patients were male. The prevalence of hypertension, diabetes mellitus and dyslipidemia were 29.8%, 18.8% and 11.8%. Coronary CT showed epicardial stenosis of greater than 50% in 299 (5.4%) patients. When patients were grouped according to the degree of epicardial stenosis, 4,027 (72.4%) patients had no epicardial stenosis, 1,118 (20.1%) patients had less than 50% stenosis, 225 (4.0%) patients had 50-70% stenosis or left main lesion of less than 50%, and 146 (2.6%) patients had greater than 70% epicardial stenosis or greater than 50% left main disease. During mean follow up period of 681짹315 days, 347 (6.2%) patients had cardiovascular events, with mean time to event of 663짹475 days. Clinical events which included cardiac death, acute coronary syndrome, and admission due to any other heart problem such as heart failure, were present in 348 (6.3%) patients. From receiving operator curves, epicardial stenosis from coronary CT showed greatest area under curve for predicting clinical events (Table). Conclusion: The degree of epicardial stenosis, an imaging parameter from coronary CT, showed best predictive value in predicting cardiovascular outcome, when compared to clinical parameters.