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Factors affecting the Change of Left Atrial Volume in Acute Myocardial Infarction
가톨릭대학교
정수연, 윤호중, 김지희, 엄재선, 조정선, 김미정, 박찬석, 조은주, 정해억, 전희경
Objective: The left atrial volume (LAV) is an important prognostic factor in cardiovascular disease. However, in acute myocardial infarction (AMI), the factors affecting the changes in LAV index (ΔLAVi) has not been established yet. Methods: In one hundred eight subjects (M:F = 74:34; mean age, 62 ± 13 years) with AMI transthoracic echocardiogram was followed up at baseline and 20 months after AMI. The clinical and echocardiographic parameters related to ΔLAVi were analysed. Results: The mean ΔLAVi was 7.94 ± 9.10 mL/m2. ΔLAVi is related to the history of hypertension (r=0.197, p=0.040), fasting blood glucose (FBG) at baseline (r=0.310, p=0.001), E-wave velocity at baseline (r=-0.209, p=0.030), the change of E/E’ (r=0.246, p=0.011) and the change of LVEF (ΔEF) (r=-0.214, p=0.026). Based on multivariate analysis, FBG, E wave velocity at baseline and ΔEF were closely related to ΔLAVi (Table). Conclusions: LA remodeling after AMI is related to clinical and hemodynamic parameters such as FBG, diastolic function and systolic function. Key words: change of LA volume index, LA remodeling, AMI,

Table . Univariate and multivariate linear regression  

 

Univariate
OR

 

 

Multivariate
OR

 

 

95% CI

P value

95% CI

P value

FBG

0.31

0.042~0.162

0.001

0.258

0.025-0.145

0.006

E-wave velocity

-0.209

-38.927~-2.034 

0.03

-0.183

-38.927~-2.034 

0.047

ΔEF

-2.14

-0.700~-0.046

0.026

-0.185

-0.636~-0.007

0.045

FBG: fasting blood glucose, ΔEF: the change of LVEF, OR: odds ratio



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