мȸ ǥ ʷ

ǥ : ȣ - 540897   271 
Correlation of Cardiac Biomarker with Quantitative Analysis of Cardiovascular Magnetic Resonance Imaging in ST-elevation Myocardial Infarction
고려대학교 안암병원 순환기내과
김제상, 안철민, 박재형, 홍순준, 임도선
Background : C-reactive protein (CRP) and peak creatine kinase-MB (CK-MB) level are independent predictors of mortality in ST-elevation myocardial infarction(STEMI). Infarct size and the presence and extent of microvascular obstruction (MVO) measured by cardiovascular magnetic resonance (CMR) in myocardial infarction are associated with adverse ventricular remodeling and clinical outcome. The aim of this study is to analyze correlation of cardiac biomarker with quantitative analysis of CMR in ST-elevation Myocardial infarction. Method : The study included total 13 patients with STEMI who underwent primary PCI. We measured biomarker including peak CK-MB, CRP, and MVO volume and infarct size by CMR. The association between biomarker and quantitative measurement by CMR was analyzed by Spearman’s rank correlation coefficient. Results : Eleven patients were male. The most frequent infarct related vessel was left anterior descending coronary artery (n=9). TIMI 3 flow were recovered in most of patients (n=12). Peak CK-MB, CRP level, infarct size and MVO volume were widely distributed (168±121ng/mL, 29.9±23.1mg/L, 27.6±14.7cm3, and 3.63±2.41cm3, respectively). Peak CK-MB is correlated with MVO volume (p<0.007) but not with infarct size (p=0.65). CRP, by contrast, is correlated with infarct size (p=0.001) but not with MVO volume (p=0.79). Conclusion : This data showed the possibility of correlation between biomarker and volumetric measurements by CMR affecting long term prognosis of myocardial infarction though more data need to be accumulated.


[ư]


logo 학술대회일정 사전등록안내 초록등록안내 초록등록/관리 숙박 및 교통 안내 전시 및 광고