Introduction: Carotid IMT is surrogate markers of cerebro-cardio vascular event (CCVE) in old age. We evaluated whether thickened carotid IMT in young patients predicts the future event(CCVE) by the large cohort long-term follow-up data. Method: Among the 3920 patients (male: female=2527:1393,mean age=65짹19), Long-term outcomes of relative young age(<50 years) were analyzed. Total 315 patients(mean age= 42짹7 years, male=76.3%) were divided into quartile groups along the right maximal and mean carotid IMT. Mean follow up duration was 41짹17months. CCVE were including the stroke, cardiac death, nonfatal myocardial infarction. We compare the incidence of CCVE between the highest and lowest quartile groups during the follow-up period. Results: The range of right maximal and mean IMT in the four quartile groups(IQR) were showed (table 1). Kaplan-Meier Survival analysis showed that there were no significant differences in CCVE between highest and lowest IQR groups Conclusion: Carotid IMT was not predictive of future cerebro -cardiovascular events in the relatively young patients. Clinical significance of carotid IMT in the young patients might be different from elderly patients