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The Effect of Prediabetes in 4-year Outcomes after Percutaneous Coronary Intervention
계명대학교 의과대학 동산의료원 심장내과
신홍원, 최상웅, 배한준, 이호명, 조현옥, 조윤경, 박형섭, 윤혁준, 김형섭, 남창욱, 허승호, 김윤년, 김권배
Backgrounds: Diabetes is well known as a poor prognostic factor after percutaneous coronary intervention (PCI). The American Diabetes Association advised that an HbA1c range of 5.7–6.4 (prediabetes) should be considered as a high risk for future DM. The aim of this study was to evaluate the effect of prediabetes in long-term clinical outcomes after PCI in coronary artery disease. sup>
Methods: 382 patients without known/unknown diabetes were evaluated HbA1c and underwent PCI. By using new ADA criteria, patients were classified into two groups: prediabetic group (HbA1c: 5.7-6.4%, n=149), nondiabetic group (HbA1c<5.7%, n=233). Major adverse cardiac events (MACE: the composite of cardiac death, myocardial infarction and target-vessel revascularization) were evaluated for 4 years.
Results: There was no significant difference between two groups in risk factors and procedural data except higher number of implanted stents in prediabetes group (1.7±1.6 vs. 1.4±1.4, p=0.033) MACE was not different between two groups for 4 years (9.7% vs. 10.7%, p=0.78); death, 3.0% vs. 2.3%, p=0.70; myocardial infarction, 2.2% vs. 1.9%, p=0.81; target vessel revascularization, 8.2% vs. 9.3%, p=0.65. Prediabetes was not a predictor for adverse clinical outcomes. Kaplan-Meyer curve was presented in figure.
Conclusions: Prediabetes was not a poor prognostic factor for long term clinical outcomes after PCI.
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