^{Background: Ventriculo-arterial coupling (VAC) usually provide the pathophysiology of interaction in the cardiovascular contractility system. However, there are limited data regarding relationship between VAC and 24hr-ambulatory blood pressure (ABPM) monitoring. We sought to compare VAC and blood pressure parameters, in addition to cardioankle vascular index (CAVI) in hypertension patients.
Methods: In thirty one hypertensive patients, VAC was estimated non-invasively by echocardiography, and CAVI was also obtained in the same study day. In addition, ABPM data was gathered including ambulatory arterial stiffness index (AASI). We examined the association between VAC, ABPM, and CAVI.
Results: VAC was significantly correlated with age (R=0.517, p<0.001), nocturnal systolic non-dipping (R=0.372, p=0.043), nocturnal diastolic non-dipping (R=0.401, p=0.028), ABSI (R=0.624, p<0.001), and CAVI (R=0.550, p=0.002). In multiple linear regression analysis, independent predictors of VAC were ABSI (棺=0.245, p=0.001) and CAVI (棺=0.018, p=0.009).
Conclusion: ABSI could be not only a parameter of arterial stiffness but also the most determinant of VAC in hypertensive patients.}