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ȣ - 550266 403 |
| Comparison of 12-month Clinical Outcomes in Patients with Chronic Total Occlusion (CTO) Lesion between Diabetic and Non-Diabetic: A Multicenter Study of e-CTO Investigators |
| 고려대학교 구로병원 심혈관 센터¹, e-CTO investigators² |
| 최철웅¹, Amro Elnagar¹, 김선원¹, 임성일¹,나진오¹,임홍의¹, 김진원¹,김응주¹,한성우¹, 나승운¹, 박창규¹,서홍석¹, 오동주¹, 최진호² , 권현철² ,김희열² ,안영근², 유철웅², 조정래² ,허승호², 배장호², 이재웅², 김두일², 박종선², 배장호², 조장현², 김경수² ,강웅철², 이승진², 이재환², 조병렬², 강태수², 전동운² ,이승환², 박종선², 채인호², 최동훈², 홍범기², 김효수², 김무현², 임도선², 채제건², 김명곤², 박헌식², 장양수² |
Backgrounds: The aim of this study is to compare the one year clinical outcomes in patients with chronic total occlusion (CTO) lesion between diabetic and non-diabetic.
Methods: A total 3890 patients (Age; 62.99 ± 11.04, Men; 74.1 %) with chronic total occlusion were analyzed. The patients were divided into a diabetic group (n = 2,579 patients) and a non-diabetic group (n = 1,401 patients).We evaluated the one year clinical outcomes including target lesion revascularization (TLR) and major adverse cardiac events (MACEs) between the two groups.
Results: One year after PCI, 93 All-MACEs were developed. TLR and All-MACEs was higher in diabetic group compared with that in non-diabetic group (respectively, 1.8 % vs. 3.1%, p = 0.042 and 3.4 % vs. 5.1%, p = 0.043). In multivariate analysis, diabetic mellitus was an independent predictor for one year TLR (OR; 1.847, p=0.034) and All-MACEs (OR; 1.707, p=0.015).
Conclusion: This study identified diabetic mellitus as an independent risk factor for one year TLR and All-MACEs in patients with CTO lesion.
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Table. Odds ratios of risk factors for 12-month TLR and All-MACEs in multivariate analysis.
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OR for 12-month TLR |
p |
OR ratio for 12-month All-MACEs |
p |
|
Age |
1.014(0.986-1.042) |
0.784 |
1.011(0.990-1.032) |
0.297 |
|
PCI Hx |
0.807(0.420-1.551) |
0.520 |
0.788(0.479-1.296) |
0.348 |
|
Male |
1.096(0.571-2.102) |
0.784 |
0.916(0.564-1.487) |
0.723 |
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HTN |
0.745(0.415-1.339) |
0.325 |
0.536(0.347-1.025) |
0.356 |
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DM |
1.847 (1.048-3.255) |
0.034 |
1.707(1.109-2.627) |
0.015 |
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