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Clinical Outcomes of Patients with Acute Aortic Intramural Hematoma according to Stanford Classification; Multicenter Registry study for 2 years
영남대학교병원 순환기내과¹ , 계명대학교 동산병원 순환기내과 ², 대구 카톨릭대학교병원 순환기 내과³ , 대구 파티마병원 순환기내과⁴
강상욱¹ , 박종선¹ , 김유민¹ , 박원종¹ , 이상희¹ , 김웅¹ , 홍그루¹ , 신동구¹ , 김영조¹ , 이호명² , 조윤경² , 허승호² , 남창욱² , 홍승표³, 이진배³, 류재근³, 최지용³, 김기주⁴, 이봉렬⁴, 정병천⁴
Backgrounds: Intramural hematoma of the aorta (IMH) evolves very dynamically in the short term reabsorption, classical dissection, or aortic rupture. The aim of this study was to evaluate the clinical outcomes and morphological evolution according to Stanford classification. Material and Methods: We analyzed 118 consecutive medically treated patients with acute IMH from four large centers in Daegu. The patients were grouped according to Stanford classification. Type A IMH were 44 (37.3%) and type B IMH were 74(62.7%). A follow-up contrast enhanced computed tomography (CT) was performed in 89 (75.4%) patients within 30 days. Clinical outcomes such as death, surgical conversion and morphological evolution by CT were analyzed. Results: In-hospital mortality rate were not different between type A and type B IMH (3/44, 6.8% vs. 2/74, 2.7%, p=0.36). The follow-up CT study showed that intramural hematoma was resorbed in 20 patients with type A IMH and in 36 patients with type B (20/35, 57.1% vs. 36/54, 66.7%, p=0.194). Progression to aortic dissection was common with type A comparing type B IMH (6/44, 13.6% vs. 2/74, 2.7%, p=0.051). Surgical conversion was more needed because of aortic dissection or progressive aortic dilatation in type A IMH (6/44, 13.6% vs. 1/74, 1.4%, p=0.011). Mean follow-up duration was 877±906 days. The 2-year survival rate was 81.8% in the type A IMH and 87.8% in the type B IMH (p=0.421). Conclusion: Initial medical treatment and timely surgical intervention showed similar clinical outcomes in both types of acute IMH. But, large randomized trial is needed to clarify the optimal treatment modalities of acute IMH. Key Words : Intramural hematoma, clinical outcomes, morphological evolution


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