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Impact of Home-based Exercise Training with Wireless Monitoring in Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention
계명의대 심장내과¹, 대구대학교 물리치료학과²
이영화¹ , 허승호¹ ,조윤경¹,박형섭¹ , 윤혁준¹, 김형섭¹, 남창욱¹, 김윤년¹, 김권배¹, 김 경²
Background: Recent studies have suggested the favorable effect of cardiac rehabilitation (CR) in patients with cardiovascular disease. But little is known about the impact of the CR on patients with acute coronary syndrome (ACS). The purpose of this study was to evaluate the effect of home-based exercise training with wireless monitoring in ACS patients. Methods: A total of 41 ACS patients who underwent PCI were prospectively enrolled. According to performing CR, all patients were randomly divided into 2 groups; CR and usual care (UC) groups. The CR group received the home-based exercise training (5 times per week for walking and 1 to 2 times for treadmill exercise) under wireless monitoring, whereas diet control, medications, and/or self-based exercise were performed in the UC group. The CR program was started within a week after PCI and maintained for 3 months. The exercise capacity, high-sensitivity C-reactive protein (hs-CRP), echocardiograhic parameters, and quality of life (QOL) questionnaire were evaluated at baseline and 3 months follow-up. Results: Baseline clinical characteristics were similar between the 2 groups. From baseline to 3 months follow-up, there were significant improvements of RPPsubmax, RPEsubmax, METs, ETmax, LVEF, and RWMA in both groups (p<0.05 for all). Compared to the UC group, the CR group showed favorable results in terms of RPPsubmax, RPEsubmax, METs, ETmax, and QOL (p<0.05 for all) at 3 months follow-up (see the table). Conclusion: Although the improvements of exercise capacity, echocardiogaphic findings, and QOL were observed in both groups, CR using home-based exercise training with wireless monitoring likely showed more favorable effects in ACS patients undergoing PCI.

CR (n = 20)

UC (n = 21)

baseline

after 3 months

baseline

after 3 months

RPPsubmax, mmHgbpm

162.9±41.4

132.0±24.0*

176.1±47.2

152.7±40.2*

RPEsubmax, mmHgbpm

10.40±1.93

8.50±1.88*

11.29±2.63

9.80±2.25*

METs

7.03±1.88

9.70±1.87*

6.72±2.20

8.22±2.21*

ETmax, sec

660.4±160.8

846.3±109.0*

649.8±156.7

746.8±138.6*

hs-CRP, mg/l

0.39±0.67

0.04±0.06*

0.48±0.91

0.24±0.70

LVEF, %

52.35±10.13

60.35±10.34*

53.38±8.35

60.67±10.43*

RWMA

1.36±0.41

1.10±0.18*

1.25±0.30

1.14±0.26*

QOL

57.80±4.99

60.05±5.81*

56.43±6.56

56.90±5.00

Values are presented as mean ± SD; *p<0.05, comparison between baseline and 3 months follow-up;†p<0.05, compare-son of CR group versus UC group; RPPsubmax is defined as rate pressure product at stage by modified bruce protocol ; RPEsubmax is defined as rate of perceived exertion at stage by modified bruce protocol; METs is defined as metabolic equivalent of the task; ETmax is defined as maximal exercise time



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