^{backgrounds: Current treatment guideline for multivessel coronary artery disease (MVD) including left anterior descending artery (LAD) and/or left main disease (LMD) recommends coronary artery bypass surgery (CABG). However, large portion of these patients underwent percutaneous coronary intervention (PCI) with drug-eluting stent (DES). We would like to evaluate the long-term clinical outcome after PCI in patients with MVD and/or LMD.
Methods: 604 consecutive patients who underwent PCI with DES in MVD with LAD and/or LM, retrospectively. Patients were divided according stented vessels as 4 groups; LM only, 2 vessels with LAD, 3 vessels, and MVD with LM. Major adverse cardiac events (defined as cardiac death, myocardial infarction (MI), target lesion revascularization (TLR), and stent thrombosis (ST)) were evaluated for 2 years after index procedure.
Results: The 2-year MACE in overall population was 12.7% (77/604): cardiac death 2.2%, MI 2.8%, TLR 7.3%, and ST 1.3%. The MACE in LM only group was 4.3%, in 2 vessels with LAD group 12.1%, in 3 vessels group 14.9%, and in MVD with LM group 19.5%. The survival curve of 4 groups is shown below figure.
Conclusion: Although the MACE rate increased according to the severity of coronary artery disease, overall MACE was relatively acceptable. PCI can be another option in the selected patients with current CABG indicated disease, especially in LM only or 2 vessel disease with LAD.}