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ȣ - 550806 61 |
| Diastolic but not systolic blood pressure was more significantly affected by the gender in newly diagnosed hypertensive patients with obesity |
| 전남대병원¹ , 관동대제일병원2, 서울아산병원3, 인하대병원4, 충북대병원5, 서울삼성병원6, 고대 구로병원7, 건양대병원8, 연세 세브란스병원9, 아주대병원9, 서울 성모병원11, 강남세브란스병원12, 분당서울대병원13 |
| 윤현주¹ , 안영근1, 김계훈1, 박종춘1, 박정배2, 강덕현3, 권준4, 김동운5, 박승우6, 박창규7, 배장호8, 성지동9, 신준한10, 윤호중11, 임세중12, 최동주13 |
Background: Obesity is associated with an increased risk of cardiovascular morbidity and mortality as well as life of quality. Body mass index (BMI) provided the most useful parameter of obesity. The aim of this study, we tried to search the differences in certain well-defined blood pressure pattern according to gender between obese and non-obese patients in newly diagnosed hypertensive patients.
Methods: Total 773 hypertensive patients (442 male, 48±11year) enrolled from Korean Hypertesion Network II were evaluated in this study. The patients were no history of hypertensive medication. BP was checked by nurse or doctor in office, self measurement in home and ambulatory monitoring. The study population was divided into two groups based on their BMI (obese group ≤ 24kg/m2 and non obese group II > 25kg/m2). The mean systolic and diastolic BP for both male and female categories of patients were compared between two groups.
Results: In female, there was no significant difference of systolic and diastolic BP measured in office, home and ambulatory monitoring between groups. In male gender, there was no significant systolic BP difference measured in office, home and ambulatory monitoring between groups. Mean diastolic BP in office (97±12 vs. 94±11mmHg, p=0.016), average diastolic BP in AM at home (92± 14 vs. 88±11mmHg, p=0.017), average diastolic BP in PM at home (90±14 vs. 86±11mmHg, p=0.010) and mean diastolic BP in home (91±12 vs. 87±11mmHg, p=0.005) were significantly higher in obese group than non-obese group. There was no significant difference in BP pattern between obese and non-obese group obtained from ambulatory monitoring. Although there was no clinical significance, diastolic mean BP from all measurement included office, home and ambulatory monitoring was higher in obese group than in non obese group (92±10 vs. 90±10mmHg, p=0.068). Night time heart rate (64±9.5 vs. 61±8.6 mmHg, p=0.026) from ambulatory BP and mean heart rate from all measurement (74±8.6 vs. 71±8.9 mmHg, p=0.026) were higher in obese group than non-obese group in hypertensive patients.
Conclusions: Diastolic but not systolic blood pressure was more significantly affected by the gender in newly diagnosed hypertensive patients with obesity
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