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| The influences of obesity in circadian blood pressure pattern in Koreans form KOR-ABP registry |
| 이화의대¹ , 한양의대² , 전남의대³ , 연세의대⁴ , 가톨릭의대5 , 서울의대6 , 경희의대7 |
| 편욱범¹ , 신진호² , 김주한³ , 박성하⁴ , 임상현5 , 김광일6 , 김우식 7, 김순길 ² |
Backgrouds; Obesity has a lot of metabolic influences including blood pressure, glucose, lipid and inflammatory factors. There were evidences of different circadian blood pressure patterns according to BMI and it will help to tailored treatment strategies for blood pressure control in obesity.
Methods; Total 1928 subjects were evaluated the circadian blood pressure patterns with ambulatory blood pressure monitoring from Kor-ABP registry. Age was 56.1±14.4 years old and
50.9% of subjevts were female. Daytime and nocturnal blood pressure were calculated using narrow fixed time interval method. Nocturnal dipping was defined as (daytime systolic BP(SBP) – nocturnal SBP)/daytime SBP. Non-dipper was defined as nocturnal dipping below 10 %. Obesity was defined with BMI>25 Kg/m2.
Results; Obese patients have higher daytime than non-obese patients (systolic BP: 138.6±16.6 Vs. 134.5±16.3 mmHg, p<0.001, diastolic BP 87.1±11.9 Vs. 84.5±11.6 mmHg, p<0.001) and higher nighttime blood pressure (systolic BP: 126.0±45.9 Vs. 126.0±27.2 mmHg, p=0.005, diastolic BP 80.6±13.8 Vs. 77.8±12.8 mmHg, p<0.001). But heart rate was not different in both groups. In our registry, non-dipper was not higher in obese subjects.
Conclusions; Ambulatory blood pressure monitoring in Korean subjects revealed that obesity increased the daytime and nighttime blood pressure but no influences in dipping patterns.
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