Background and objectives To compare the mid-tem vascular response between acute myocardial infarction (AMI) and non-AMI settings after everolimus-eluting stent (EES) implantation using optical cohererence tomography (OCT).
Methods The present study was conducted as a cross-sectional observational study with prospective OCT registry. A total 48 coronary lesions (12 AMI, 36 non-AMI) was evaluated by OCT at 12 months after EES implantation. The percentage of neointimal hyperplasia (NIH) area at every 1 mm cross section was measured. The degree of neointimal coverage and the prevalence of malapposition were compared between infarct-related and non-infarct coronary lesions.
Results The percentage of NIH and prevalence of uncovered strut were similar in both groups (Table). The prevalence of malapposition and malapposition with uncovered strut were significantly higher in infarct-related lesions than non-infarct coronary lesions (2.1짹3.1 vs. 0.5짹1.2, P=0.038 and 0.9짹1.6 vs. 0.05짹0.2, P=0.02, respectively) (Figure).
Conclusions Neoinitimal coverage occurred similarly in infarct-related and non-infarct coronary lesions. But stent malapposition developed higher in infarct-related lesions than non-infarct coronary lesions.