Backgrounds Several studies have reported the phenomenon of post-exercise hypotension. But, there are not many studies about central blood pressure (cBP) and arterial stiffness after single bout aerobic exercise. cBP, wave reflection, and arterial stiffness have been proposed as cardiovascular risk factors. We investigated the effect of single bout exercise on cBP and arterial stiffness in PCI patients. Methods Ten patients who were done PCI recently were enrolled. We measured cBP, Augmentation Index (AIx), brachial-ankle pulse wave velocity (ba-PWV) before and after single bout 1-hour supervised exercise training. Central blood pressure was measured using HEM-9000AI (Omron Healthcare, Inc. Japan). Ba-PWV was measured using VP-1000(Colin Co. Komaki, Japan). Results After 1-hour supervised exercise, blood pressure was reduced (Brachial systolic pressure, 136mmHg to 117mmHg, P=0.004, brachial diastolic pressure, 77 to 71, P=0.024). We also could see post-exercise central systolic blood pressure lowering (145mmHg to 123mmHg) (P=0.002). AIx. Improved after exercise (91% to 82%) (P=0.004). but, there is no significant change about ba-PWV. (P=0.081) (figure) Conclusions Even 1-hour single bout supervised exercise training reduce central blood pressure(cBP) and arterial stiffness. Because cBP is cardiovascular prognostic factor, even single bout exercise has cardiovascular protective effects.